people
research
publication
contact
news
links
Santiago Mateos, PhD
Reader in Cell Biology
Department of Cell Biology
University of Seville
Avda. Reina Mercedes nº 6
41012- Seville (Spain)
Phone. +34 954 554339
Fax. +34 954 610261
e-mail:smateos@us.es
:: ver temario ::
B.S.c. University of Seville, Spain 1983.
M.S.c. University of Seville, Spain 1985.
PhD. University of Seville, Spain 1989.

Santiago Mateos received his PhD. in Cellular Biology from University of Seville where we worked in Felipe Cortés´s Lab. Studying The Repair of Chromosome Damage during the G2 Phase of The Cell Cycle in Plants and Animal Cells. His post-doctoral fellowship was at School of Biological and Medical Sciences, Division of Cell and Molecular Biology at The University of St. Andrews in St. Andrews, Scotland with Dr. Peter Bryant, where he studied The molecular processes involved in the genetic and cytogenetic effects of radiation. Also he was a Human Capital and Mobility Research fellow at The Institute of Cancer Research in London with professor´s G.G. Steel and T.J. McMillan where he studied cellular radiosensitivity and DNA damage in different human tumour cell lines.

He has been Assistant Professor at University of Seville from 1989 to 2000. Nowadays, he is Reader in Cell Biology at the Department of Cell Biology of the University of Seville, in Seville , Spain.
.:: PUBLICATIONS FROM THE LAST FEW YEARS ::.
 
  click here for all publications

Cantero G, Campanella C, Mateos S, Cortes F.
Topoisomerase II inhibition and high yield of endoreduplication induced by the flavonoids luteolin and quercetin.
Mutagenesis. 2006 Sep;21(5):321-5. Epub 2006 Sep 1.
PMID: 16950806 [PubMed - indexed for MEDLINE] ------

Cantero G, Pastor N, Mateos S, Campanella C, Cortes F.
Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II.
Mutat Res. 2006 Jul 25;599(1-2):160-6. Epub 2006 Mar 30.
PMID: 16574165 [PubMed - indexed for MEDLINE] ------

Mateos S, Hajji N, Pastor N, Cortes F.
Modulation of radiation response by inhibiting topoisomerase II catalytic activity.
Mutat Res. 2006 Jul 25;599(1-2):105-15. Epub 2006 Mar 30.
PMID: 16574164 [PubMed - indexed for MEDLINE] ------

Cantero G, Mateos S, Pastor N, Cortes F.
Halogen substitution of DNA protects from poisoning of topoisomerase II that results in DNA double-strand breaks.
DNA Repair (Amst). 2006 Jun 10;5(6):667-74. Epub 2006 Jan 10.
PMID: 16406738 [PubMed - indexed for MEDLINE] ------

Mateos S, Domínguez I, Pastor N, Cantero G, Cortes F.
The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells.
Mutat Res. 2005 Oct 15;578(1-2):33-42. Epub 2005 Mar 23.
PMID: 16202795 [PubMed - indexed for MEDLINE] ------

Hajji N, Mateos S, Pastor N, Dominguez I, Cortes F.
Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor.
Mutat Res. 2005 May 2;583(1):26-35.
PMID: 15866463 [PubMed - in process] ------

Cortes F, Mateos S, Pastor N, Dominguez I.
Toward a comprehensive model for induced endoreduplication.
Life Sci. 2004 Nov 26;76(2):121-35. Review.
PMID: 15519359 [PubMed - indexed for MEDLINE] ------

Hajji N, Pastor N, Mateos S, Dominguez I, Cortes F.
DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193.
Mutat Res. 2003 Sep 29;530(1-2):35-46.
PMID: 14563529 [PubMed - indexed for MEDLINE] ------

Cortes F, Pastor N, Mateos S, Dominguez I.
The nature of DNA plays a role in chromosome segregation: endoreduplication in halogen-substituted chromosomes.
DNA Repair (Amst). 2003 Jun 11;2(6):719-26.
PMID: 12767350 [PubMed - indexed for MEDLINE] ------

Pastor N, Jose Flores M, Dominguez I, Mateos S, Cortes F.
High yield of endoreduplication induced by ICRF-193: a topoisomerase II catalytic inhibitor.
Mutat Res. 2002 Apr 26;516(1-2):113-20.
PMID: 11943617 [PubMed - indexed for MEDLINE] ------

Pastor N, Dominguez I, Mateos S, Cortes F.
A comparative study of genotoxic effects of anti-topoisomerase II drugs ICRF-193 and bufalin in Chinese hamster ovary cells.
Mutat Res. 2002 Mar 25;515(1-2):171-80.
PMID: 11909765 [PubMed - indexed for MEDLINE] ------

Dominguez I, Pastor N, Mateos S, Cortes F.
Testing the SCE mechanism with non-poisoning topoisomerase II inhibitors.
Mutat Res. 2001 Oct 18;497(1-2):71-9.
PMID: 11525909 [PubMed - indexed for MEDLINE] ------

McMillan TJ, Tobi S, Mateos S, Lemon C.
The use of DNA double-strand break quantification in radiotherapy.
Int J Radiat Oncol Biol Phys. 2001 Feb 1;49(2):373-7.
PMID: 11173130 [PubMed - indexed for MEDLINE] ------

Dominguez I, Mateos S, Cortes F.
Related Articles, Links
Yield of SCEs and translocations produced by 3 aminobenzamide in cultured Chinese hamster cells.
Mutat Res. 2000 Mar 14;448(1):29-34.
PMID: 10751620 [PubMed - indexed for MEDLINE] ------

Valenzuela MT, Mateos S, Ruiz de Almodovar JM, McMillan TJ.
Variation in sensitizing effect of caffeine in human tumour cell lines after gamma-irradiation.
Radiother Oncol. 2000 Mar;54(3):261-71.
PMID: 10738085 [PubMed - indexed for MEDLINE] ------

Department of Cell Biology - University of Seville Avda. Reina Mercedes 6, 41012 SEVILLE (Spain)
 diseño: cristinameneses.com