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Inmaculada Domínguez, PhD
Reader in Cell Biology
Department of Cell Biology
University of Seville
Avda. Reina Mercedes nº 6
41012- Seville (Spain)
Phone. +34 954 5599499
Fax. +34 954 610261
e-mail: idomin@us.es
:: ver temario ::
B.S.c. University of Seville, Spain 1988
PhD. University of Seville, Spain 1993

Inmaculada Domínguez has been working in Felipe Cortés´lab
since 1989.

She spent three months at the National Defence Research Establishment (FOA) in Umea (Suecia) working on the role of glutatión peroxidase in the protection to oxidative damage induced by hydrogen peroxide and gamma ray.

In 1993 she received her PhD from University of Sevilla working on adaptive response and the role of antioxidant enzymes in the protection of DNA damage caused by ionising radiation in eucaryotic cells.

She got a post-doctoral fellowship from European Community and Fundación Ramón Areces to work in the Department of Radiation Genetics and Chemical Mutagenesis, Faculty of Medicine , University of Leiden. During this period she carried out work on Obtention of whole chromosome probes for Cricetulus grisesu and its use for detection by FISH of spontaneous and radiation-induced chromosome rearrangements.

She has been Assistant Professor at University of Seville from 1995 to 2002. Nowadays, she is Reader in Cell Biology at the Department of Cell Biology of the University of Seville, in Seville , Spain.
.:: PUBLICATIONS FROM THE LAST FEW YEARS ::.
 
  click here for all publications

Mateos S, Domínguez I, Pastor N, Cantero G, Cortes F.
The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells.
Mutat Res. 2005 Oct 15;578(1-2):33-42. Epub 2005 Mar 23.
PMID: 16202795 [PubMed - indexed for MEDLINE] ------

Hajji N, Mateos S, Pastor N, Dominguez I, Cortes F.
Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor.
Mutat Res. 2005 May 2;583(1):26-35.
PMID: 15866463 [PubMed - in process] ------

Cortes F, Mateos S, Pastor N, Dominguez I.
Toward a comprehensive model for induced endoreduplication.
Life Sci. 2004 Nov 26;76(2):121-35. Review.
PMID: 15519359 [PubMed - indexed for MEDLINE] ------

Hajji N, Pastor N, Mateos S, Dominguez I, Cortes F.
DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193.
Mutat Res. 2003 Sep 29;530(1-2):35-46.
PMID: 14563529 [PubMed - indexed for MEDLINE] ------

Cortes F, Pastor N, Mateos S, Dominguez I.
The nature of DNA plays a role in chromosome segregation: endoreduplication in halogen-substituted chromosomes.
DNA Repair (Amst). 2003 Jun 11;2(6):719-26.
PMID: 12767350 [PubMed - indexed for MEDLINE] ------

Pastor N, Jose Flores M, Dominguez I, Mateos S, Cortes F.
High yield of endoreduplication induced by ICRF-193: a topoisomerase II catalytic inhibitor.
Mutat Res. 2002 Apr 26;516(1-2):113-20.
PMID: 11943617 [PubMed - indexed for MEDLINE] ------

Pastor N, Dominguez I, Mateos S, Cortes F.
A comparative study of genotoxic effects of anti-topoisomerase II drugs ICRF-193 and bufalin in Chinese hamster ovary cells.
Mutat Res. 2002 Mar 25;515(1-2):171-80.
PMID: 11909765 [PubMed - indexed for MEDLINE] ------

Dominguez I, Pastor N, Mateos S, Cortes F.
Testing the SCE mechanism with non-poisoning topoisomerase II inhibitors.
Mutat Res. 2001 Oct 18;497(1-2):71-9.
PMID: 11525909 [PubMed - indexed for MEDLINE] ------

Dominguez I, Mateos S, Cortes F.
Related Articles, Links
Yield of SCEs and translocations produced by 3 aminobenzamide in cultured Chinese hamster cells.
Mutat Res. 2000 Mar 14;448(1):29-34.
PMID: 10751620 [PubMed - indexed for MEDLINE] ------

F. Cortés, N. Pastor, S. Mateos, I. Domínguez
Roles of DNA topoisomerases in chromosome segregation and mitosis
Reviews in Mutation Research, 543: 59-66 (2003) ------

N. Hajji, S. Mateos, N. Pastor, I. Domínguez, F. Cortés.
Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor.
Mutat. Res., 583: 26-35 (2005) ------

Department of Cell Biology - University of Seville Avda. Reina Mercedes 6, 41012 SEVILLE (Spain)
 diseño: cristinameneses.com