Publicaciones recientes

2024
Protective effect of sucrose esters from cape gooseberry (Physalis peruviana L.) in TNBS-induced colitis. Ocampo YC, Castro JP, Pájaro IB, Caro D, Talero E, Motilva V, Franco LA.  PLoS One. 2024 Mar 21;19(3):e0299687. doi: 10.1371/journal.pone.0299687.
Photoprotective Effects of Two New Morin-Schiff Base Derivatives on UVB-Irradiated HaCaT Cells. García-Gil S, Rodríguez-Luna A, Ávila-Román J, Rodríguez-García G, Del Río RE, Motilva V, Gómez-Hurtado MA, Talero E. Antioxidants (Basel). 2024 Jan 22;13(1):134. doi: 10.3390/antiox13010134.
Functional features of the exopolysaccharide extracts produced by Lactiplantibacillus strains isolated from table olives. López-García E, Marín-Gordillo A, Sánchez-Hidalgo M, Ávila-Román J, Romero-Gil V, Bermúdez-Oria A, Benítez-Cabello A, Garrido-Fernández A, Rodríguez-Gómez F, Arroyo-López FN. Food Funct. 2024 Feb 19;15(4):1938-1947. doi: 10.1039/d3fo04223e.
Exploring Metabolic and Gut Microbiome Responses to Paraquat Administration in Male Wistar Rats: Implications for Oxidative Stress. Hernandez-Baixauli J, Chomiciute G, Tracey H, Mora I, Cortés-Espinar AJ, Ávila-Román J, Abasolo N, Palacios-Jordan H, Foguet-Romero E, Suñol D, Galofré M, Alcaide-Hidalgo JM, Baselga-Escudero L, Del Bas JM, Mulero M. Antioxidants (Basel). 2024 Jan 1;13(1):67. doi: 10.3390/antiox13010067.

2023
Abrupt Photoperiod Changes Differentially Modulate Hepatic Antioxidant Response in Healthy and Obese Rats: Effects of Grape Seed Proanthocyanidin Extract (GSPE). Cortés-Espinar AJ, Ibarz-Blanch N, Soliz-Rueda JR, Calvo E, Bravo FI, Mulero M, Ávila-Román J. Int J Mol Sci. 2023 Dec 2;24(23):17057. doi: 10.3390/ijms242317057.
Rhythm and ROS: Hepatic Chronotherapeutic Features of Grape Seed Proanthocyanidin Extract Treatment in Cafeteria Diet-Fed Rats. Cortés-Espinar AJ, Ibarz-Blanch N, Soliz-Rueda JR, Bonafos B, Feillet-Coudray C, Casas F, Bravo FI, Calvo E, Ávila-Román J, Mulero M. Antioxidants (Basel). 2023 Aug 12;12(8):1606. doi: 10.3390/antiox12081606.
9-PAHPA long term intake in DIO and db/db mice ameliorates insulin sensitivity but has few effects on obesity and associated metabolic disorders. Bonafos B, Cortés-Espinar AJ, Balas L,  Pessemesse L, Lambert K, Benlebna M, Gaillet S, Pelletier F, Delobel P, Ávila-Román J, Abellán MM, Bertrand-Gaday C, Durand T, Coudray C, Casas F, Feillet-Coudray C. J Nutr Biochem. 2023 Feb;112:109216. doi: 10.1016/j.jnutbio.2022.109216.
Photoperiod Conditions Modulate Serum Oxylipins Levels in Healthy and Obese Rats: Impact of Proanthocyanidins and Gut Microbiota. Arreaza-Gil V, Ávila-Román J, Escobar-Martínez I, Muguerza B, Suárez M, Arola-Arnal A, Torres-Fuentes C. Nutrients. 2023 Jan 30;15(3):707. doi: 10.3390/nu15030707.
Up-Regulation of the Nrf2/HO-1 Antioxidant Pathway in Macrophages by an Extract from a New Halophilic Archaea Isolated in Odiel Saltworks. Ávila-Román J, Gómez-Villegas P, de Carvalho CCCR, Vigara J, Motilva V, León R, Talero E. Antioxidants (Basel). 2023 May 11;12(5):1080. doi: 10.3390/antiox12051080.

2022
Time-of-Day Circadian Modulation of Grape-Seed Procyanidin Extract (GSPE) in Hepatic Mitochondrial Dynamics in Cafeteria-Diet-Induced Obese Rats. Rodríguez RM, Cortés-Espinar AJ, Soliz-Rueda JR, Feillet-Coudray C, Casas F, Colom-Pellicer M, Aragonès G, Ávila-Román J, Muguerza B, Mulero M, Salvadó MJ. Nutrients. 2022 Feb 12;14(4):774. doi: 10.3390/nu14040774.
Cardioprotective Properties of Phenolic Compounds: A Role for Biological Rhythms. Torres-Fuentes C, Suárez M, Aragonès G, Mulero M, Ávila-Román J, Arola-Arnal A, Salvadó MJ, Arola L, Bravo FI, Muguerza B. Mol Nutr Food Res. 2022 Mar 13:e2100990. doi: 10.1002/mnfr.202100990.

2021
Anti-Inflammatory Effects of Rosmarinic Acid-Loaded Nanovesicles in Acute Colitis through Modulation of NLRP3 Inflammasome. Marinho S, Illanes M, Ávila-Román J, Motilva V, Talero E. Biomolecules. 2021 Jan 26;11(2):162. doi: 10.3390/biom11020162.
Preparation and In Vivo Evaluation of Rosmarinic Acid-Loaded Transethosomes After Percutaneous Application on a Psoriasis Animal Model. Rodríguez-Luna A, Talero E, Ávila-Román J, Romero AMF, Rabasco AM, Motilva V, González-Rodríguez ML. AAPS PharmSciTech. 2021 Mar 12;22(3):103. doi: 10.1208/s12249-021-01966-3.
Impact of gut microbiota on plasma oxylipins profile under healthy and obesogenic conditions. Ávila-Román J, Arreaza-Gil V, Cortés-Espinar AJ, Soliz-Rueda JR, Mulero M, Muguerza B, Arola-Arnal A, Arola L, Torres-Fuentes C. Clin Nutr. 2021 Apr;40(4):1475-1486. doi: 10.1016/j.clnu.2021.02.035.
Enzyme-Assisted Extraction to Obtain Phenolic-Enriched Wine Lees with Enhanced Bioactivity in Hypertensive Rats. López-Fernández-Sobrino R, Margalef M, Torres-Fuentes C, Ávila-Román J, Aragonès G, Muguerza B, Bravo FI. Antioxidants (Basel). 2021 Mar 26;10(4):517. doi: 10.3390/antiox10040517.
Blood Pressure-Lowering Effect of Wine Lees Phenolic Compounds Is Mediated by Endothelial-Derived Factors: Role of Sirtuin 1. López-Fernández-Sobrino R, Soliz-Rueda JR, Ávila-Román J, Arola-Arnal A, Suárez M, Muguerza B, Bravo FI. Antioxidants (Basel). 2021 Jul 3;10(7):1073. doi: 10.3390/antiox10071073.
Anti-Inflammatory and Anticancer Effects of Microalgal Carotenoids. Ávila-Román J, García-Gil S, Rodríguez-Luna A, Motilva V, Talero E. Mar Drugs. 2021 Sep 23;19(10):531. doi: 10.3390/md19100531.
Preparation, Characterization and Evaluation of the Anti-Inflammatory Activity of Epichlorohydrin-β-Cyclodextrin/Curcumin Binary Systems Embedded in a Pluronic®/ Hyaluronate Hydrogel. Fernández-Romero AM, Maestrelli F, García-Gil S, Talero E, Mura P, Rabasco AM, González-Rodríguez ML. Int J Mol Sci. 2021 Dec 17;22(24):13566. doi: 10.3390/ijms222413566.

2020
New Eunicellin-Type Diterpenes from the Panamanian Octocoral Briareum Asbestinum. Gutiérrez M, Santamaría R, Gómez-Reyes JF, Guzmán HM, Ávila-Román J, Motilva V, Talero E. Mar Drugs. 2020 Jan 27;18(2):84. doi: 10.3390/md18020084.
Modulation of Food Intake by Differential TAS2R Stimulation in Rat. Grau-Bové C, Miguéns-Gómez A, González-Quilen C, Fernández-López JA, Remesar X, Torres-Fuentes C, Ávila-Román J, Rodríguez-Gallego E, Beltrán-Debón R, Blay MT, Terra X, Ardévol A, Pinent M. Nutrients. 2020 Dec 10;12(12):3784. doi: 10.3390/nu12123784.
Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn’s Disease by the Regulation of Antioxidant and Anti-Inflammatory Pathways. Ortiz T, Argüelles-Arias F, Illanes M, García-Montes JM, Talero E, Macías-García L, Alcudia A, Vázquez-Román V, Motilva V, De-Miguel M. Nutrients. 2020 Jun 11;12(6):1752. doi: 10.3390/nu12061752.
Meroterpenoids from the Brown Alga Cystoseira usneoides as Potential Anti-Inflammatory and Lung Anticancer Agents. Zbakh H, Zubía E, de Los Reyes C, Calderón-Montaño JM, López-Lázaro M, Motilva V. Mar Drugs. 2020 Apr 11;18(4):207. doi: 10.3390/md18040207.
Anticancer Activities of Meroterpenoids Isolated from the Brown Alga Cystoseira usneoides against the Human Colon Cancer Cells HT-29. Zbakh H, Zubía E, Reyes CL, Calderón-Montaño JM, Motilva V. Foods. 2020 Mar 6;9(3):300. doi: 10.3390/foods9030300.

2019
Chrononutrition and Polyphenols: Roles and Diseases. Arola-Arnal A, Cruz-Carrión Á, Torres-Fuentes C, Ávila-Román J, Aragonès G, Mulero M, Bravo FI, Muguerza B, Arola L, Suárez M. Nutrients. 2019 Oct 30;11(11):2602. doi: 10.3390/nu11112602.
Fucoxanthin and Rosmarinic Acid Combination Has Anti-Inflammatory Effects through Regulation of NLRP3 Inflammasome in UVB-Exposed HaCaT Keratinocytes. Rodríguez-Luna A, Ávila-Román J, Oliveira H, Motilva V, Talero E. Mar Drugs. 2019 Aug 1;17(8):451. doi: 10.3390/md17080451.

2018
Microalgae-derived oxylipins decrease inflammatory mediators by regulating the subcellular location of NFκB and PPAR-γ. Ávila-Román J, Talero E, de Los Reyes C, García-Mauriño S, Motilva V. Pharmacol Res. 2018 Feb;128:220-230. doi: 10.1016/j.phrs.2017.10.009.
Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice. Rodríguez-Luna A, Ávila-Román J, González-Rodríguez ML, Cózar MJ, Rabasco AM, Motilva V, Talero E. Mar Drugs. 2018 Oct 10;16(10):378. doi: 10.3390/md16100378.