Name: Timothy Noel

Affiliation: University of Amsterdam

Address: Science Park 904, 1098 XH Amsterdam, The Netherlands

ORCID: 0000-0002-3107-6927

Scopus: not applicable

Short biography:

Timothy Noël is a researcher in the field of synthetic organic chemistry and technology, with a particular interest in the delicate synergy between the two fields. Tim is a Full Professor at the University of Amsterdam, where he is the Chair of Flow Chemistry. His research in the area of flow chemistry was recognized with several awards, including the DECHEMA award (2017), the Hoogewerff Youth Prize (2019), the IUPAC-ThalesNano Flow Chemistry Award (2020), the KNCV Gold Medal (2021), ERC Consolidator Grant (2022), the ACS Sustainable Chemistry & Engineering Lectureship Award (2022) and the ChemSocRev Pioneering Investigator Lectureship (2023). He was also named Fellow of the Royal Society of Chemistry in 2024. In 2025, he obtained the NWO Vici grant, which is the culmination of the NWO Talent Programme in which Prof. Noel was earlier awarded the Veni (2012) and Vidi (2015) grants – a distinction that has fallen to only a few researchers before him. He is the editor in chief of Journal of Flow Chemistry and the president of the Flow Chemistry Society.

University/Company description:

The Noel Research Group is an integral part of the Van ’t Hoff Institute for Molecular Sciences (HIMS). HIMS is dedicated to advancing the frontiers of chemistry through internationally acclaimed, curiosity-driven, and application-oriented research. Committed to leveraging its vast expertise, HIMS actively collaborates on research that addresses societal and industrial challenges. Situated in Amsterdam, the Sustainable Chemistry cluster, inclusive of Prof. Noel’s flow chemistry research group, offers a prime research setting for ongoing projects. As a Research Priority Area at the UvA, Sustainable Chemistry’s excellence is duly acknowledged and endorsed by the University Board.

Facilities, infrastructure & equipment:

The Amsterdam Science Park’s state-of-the-art research facilities (established in 2010) include advanced multinuclear NMR spectrometers (500, 400, and 300 MHz), GC and GC-MS, (Chiral) HPLC, LCMS, FT-IR, REACTIR, UV-vis and fluorescence spectrometers, stop-flow CD and UV-vis, CSI MS, EPR, and high-pressure setups for catalysis and in situ spectroscopy (HP-IR, HP-NMR).

Automated and parallel systems include RoboChem automated platforms. The flow group is equipped with precision pumps, mass flow controllers, automated back-pressure regulators, and microreactor technologies such as micromixers, photomicroreactors (e.g., in-house designs like capillary and luminescent solar concentrator based systems, as well as commercial options like Vapourtec UV 150), and gas-liquid microreactors.

Relevant publications and/or research/innovation products:

1. S. Pilon, E. Savino, O. M. Bayley, M, Vanzella, M. Claros, P. Siasiaridis, J. Liu, F. Lukas, M. Damian, V. Tseliou, N. Intini, A. Slattery, J. San Jose Orduna, T. den Hartog, R. Peters, A. F. Gargano, F. Mutti, T. Noël, “Flexible and Affordable Self-Driving Laboratory for Automated Reaction Optimization” ChemRxiv 2025, DOI: 10.26434/chemrxiv-2025-73xqf
2. A. Slattery, Z. Wen, P. Tenblad, D. Pintossi, J. Sanjose-Orduna, T. den Hartog, T. Noël, “Automated self-optimization, intensification, and scale-up of photocatalysis in flow” Science 2024, 383, eadj1817. DOI: 10.1126/science.adj1817
3. M. Bernus, D. Mazzarella, J. Stanic, Z. Zhai, A. Y. Vázquez, O. Boutureira, A. F. Gargano, T. Grossmann, T. Noël, “A modular flow platform for sulfur(VI) fluoride exchange ligation of small molecules, peptides and proteins” Nature Synthesis 2024, 3, 185-191, DOI: 10.1038/s44160-023-00441-0
4. N. Kaplaneris, M. Akdeniz, M. Fillols, F. Arrighi, F. Raymenants, G. Sanil, D. T. Gryko, T. Noël, “Photocatalytic Functionalization of Dehydroalanine-Derived Peptides in Batch and Flow” Angew. Chem. Int. Ed. 2024, e202403271, DOI: 10.1002/anie.202403271