Name: Gonzalo de Gonzalo
Affiliation: Dpto de Química Orgánica, Universidad de Sevilla (USE)
Address: c/ Profesor García González 1, 41014, Seville, Spain
ORCID: 0000-0002-0863-680X
Scopus: 7005614660
Short biography:
Prof. Dr. Gonzalo de Gonzalo, NET4FLOW coordinator, obtained his Ph.D. in Chemistry at the Universidad de Oviedo in 2003. In 2004 he performed a two-year stage at Istituto di Chimica del Riconoscimento Molecolare (Milan, Italy). In 2006, he returned to Oviedo with a Juan de la Cierva contract. In 2010 he spent one year at the University of Groningen. In 2011 he started to work at the R&D department of the pharmaceutical company Antibióticos S.A.U. In 2014 he got Ramón y Cajal contract at the University of Sevilla, obtaining in 2019 his position as Associate Professor at the University of Sevilla. His research is focused on asymmetric synthesis employing different approaches, as well as in the development of novel reaction media for carrying out (bio)catalyzed reactions. Prof. de Gonzalo has coauthored more than 95 peer-reviewed publications and patents and has a h-index of 37. He has also coedited three biocatalysis books and published 7 book chapters. He is editor-in-chief of the Pharmaceutical Section of Catalysts.
University/Company description:
The University of Sevilla is an institution that provides a public higher education service through study, teaching, and research, as well as the generation, development and dissemination of knowledge at the service of society and citizens. The dimensions and characteristics of the University of Seville make it a city within the city. This is evidenced by its campus, which has more than 26 centres and 133 departments spread throughout Seville. Its more than 70,000 students and 4,400 research and teaching members make it the second public university in Spain. The Stereoselective synthesis group, located at the Department of Organic Chemistry, has a great expertise in the asymmetric synthesis of valuable compounds employing different types of catalysts, including metal-based catalysts, organocatalysts and enzymes.
Facilities, infrastructure & equipment:
Research facilities at the Department of Organic Chemistry of the Faculty of Chemistry include several laboratories equipped with state-of-the-art technology for research in organic synthesis and applied biotransformations, required for the development of ESR05. Modern analytic (UV-Vis, GC-FID, GC-MS, FT-IR, HPLC, SFC) and characterization (NMR and HRMS) equipment is available at the research center, as well as all the standard equipment required for the development of organic synthesis, including those syntheses under protection gas (argon or nitrogen).
Relevant publications and/or research/innovation products:
- J.M. Coto-Cid, P. Rodríguez-Salamanca, C. M. Heckmann, C. E. Paul, J. López-Serrano, R. Fernández, J. M. Lassaletta, V. Hornillos, G. de Gonzalo, Asymmetric Synthesis of Atropisomeric Amines via Transaminase-Catalyzed Dynamic Kinetic Resolution, Adv. Synth. Catal. 2025, e70254. https://doi.org/10.1002/adsc.70254
- J. M. Coto-Cid, V. Hornillos, R. Fernández, J. M. Lassaletta, G. de Gonzalo, Chemoenzymatic Dynamic Kinetic Resolution of Atropoisomeric 2-(Quinolin-8-yl)benzylalcohols, J. Org. Chem. 2025, 90, 5120-5124. https://doi.org/10.1021/acs.joc.4c02996.
- G. Yang, O. Pecanac, H. Wijma, H. Rozeboom, G. de Gonzalo, M. W. Fraaije, M. L. Mascotti, Evolution of the catalytic mechanism at the dawn of the Baeyer-Villiger monooxygenases, Cell Rep. 2024, 43, 114130. https://doi.org/10.1016/j.celrep.2024.114130.
- P. Rodríguez-Salamanca, G. de Gonzalo, J. A. Carmona, J. López-Serrano, J. Iglesias-Sigüenza, R. Fernández, J. M. Lassaletta, V. Hornillos, Biocatalytic atroposelective synthesis of axially chiral N-arylindoles via Dynamic Kinetic Resolution, ACS Catal. 2023, 13, 659-664. https://doi.org/10.1021/acscatal.2c06175
- G. de Gonzalo, C. Martin, M. W. Fraaije, Positive impact of Natural Deep Eutectic Solvents on the biocatalytic performance of 5-hydroxymethyl-furfural oxidase, Catalysts, 2020, 10, 447. https://doi.org/10.3390/catal10040447