Maya Miles D, Peñate X, Sanmartín Olmo T, Jourquin F, Muñoz Centeno MC, Mendoza M, Simon MN, Chavez S, Geli V.

High levels of histones promote whole-genome-duplications and trigger a Swe1WEE1-dependent phosphorylation of Cdc28CDK1.

Elife. 2018; 7. pii: e35337. doi: 10.7554/eLife.35337.

Gutiérrez G, Millán-Zambrano G, Medina DA, Jordán-Pla A, Pérez-Ortín JE, Peñate X, Chávez S.

Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning.

Epigenetics Chromatin. 2017; 10:58. doi: 10.1186/s13072-017-0165-x.

Silva A, Cavero S, Begley V, Solé C, Böttcher R, Chávez S, Posas F, de Nadal E.

Regulation of transcription elongation in response to osmostress.

PLoS Genet. 2017; 13:e1007090. doi: 10.1371/journal.pgen.1007090.

Martínez-Fernández V, Garrido-Godino AI, Mirón-García MC, Begley V, Fernández-Pévida A, de la Cruz J, Chávez S, Navarro F.

Rpb5 modulates the RNA polymerase II transition from initiation to elongation by influencing Spt5 association and backtracking.

Biochim Biophys Acta (Gene Reg Mech) 2017; 1861:1-13. doi: 10.1016/j.bbagrm.2017.11.002. (In press)

Mena A, Medina DA, García-Martínez J, Begley V, Singh A, Chávez S, Muñoz-Centeno MC, Pérez-Ortín JE.

Asymmetric cell division requires specific mechanisms for adjusting global transcription.

Nucleic Acids Res. 2017; 45:12401-12412. doi: 10.1093/nar/gkx974.

de la Cruz J, Gómez-Herreros F, Rodríguez-Galán O, Begley V, de la Cruz Muñoz-Centeno M, Chávez S.

Feedback regulation of ribosome assembly.

Curr Genet. 2017. DOI: 10.1007/s00294-017-0764-x. (In press)

Gómez-Herreros F, Margaritis T, Rodríguez-Galán O, Pelechano V, Begley V, Millán-Zambrano G, Morillo-Huesca M, Muñoz-Centeno MC, Pérez-Ortín JE, de la Cruz J, Holstege FCP, Chávez S

The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation.

Nucleic Acids Res. 2017; 45: 9302-9318.  DOI: 10.1093/nar/gkx529.

García-Martínez J, Troulé K, Chávez S*, Pérez-Ortín JE*

Growth rate controls mRNA turnover in steady and non-steady states.

RNA Biol. 2016; 13: 1175-1181. DOI: 10.1080/15476286.2016.1236171

Chávez S*, García-Martínez J, Delgado-Ramos L, Pérez-Ortín JE*.

The importance of controlling mRNA turnover during cell proliferation.

Curr Genet. 2016; 62: 701-710. DOI: 10.1007/s00294-016-0594-2

Chávez S, Puerto-Camacho P.

Prefoldins

The Encyclopaedia of Life Sciences. 2016; DOI: 10.1002/9780470015902.a0026334

García-Martínez J, Delgado-Ramos L, Ayala G, Pelechano V, Medina DA, Carrasco F, González R, Andrés-León E, Steinmetz L, Warringer J, Chávez S*, Pérez-Ortín JE*.

The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons.

Nucleic Acids Res. 2016; 44: 3643-3658. DOI: 10.1093/nar/gkv1512.

González-Barrios M, Fierro-González JC, Krpelanova E, Mora-Lorca JA, Pedrajas JR, Peñate X, Chavez S, Swoboda P, Jansen G, Miranda-Vizuete A

Cis- and Trans-Regulatory Mechanisms of Gene Expression in the ASJ Sensory Neuron of Caenorhabditis elegans

Genetics. 2015; 200: 123-134. DOI: 10.1534/genetics.115.176172.

Nadal-Ribelles M, Mas G, Millán-Zambrano G, Solé C, Ammerer G, Chávez S, Posas F, de Nadal E

NAR Breakthrough Article: H3K4 Monomethylation Dictates Nucleosome Dynamics and Chromatin Remodeling at Stress-Responsive Genes

Nucleic Acids Research. 2015; 43: 4937-4949. doi: 10.1093/nar/gkv220

Jordán-Pla A, Gupta I, de Miguel-Jiménez L, Steinmetz LM, Chávez S*, Pelechano V*, Pérez-Ortín JE*

Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle.

Nucleic Acids Research. 2015; 43: 787-802. doi: 10.1111/jgs.13196

Delgado-Ramos L, Marcos AT, Ramos-Guelfo MS, Sánchez-Barrionuevo L, Smet F, Chávez S*, Cánovas D*.

Flow cytometry of microencapsulated colonies for genetics analysis of filamentous fungi

G3: Genes, Genomes, Genetics. 2014; 4: 2271-2278.

Mirón-García MC, Garrido-Godino AI, Martínez-Fernández V, Fernández-Pevida A, Cuevas-Bermúdez A, Martín-Expósito M, Chávez S, de la Cruz J, Navarro F.

The yeast prefoldin-like URI-orthologue Bud27 associates with the RSC nucleosome remodeler and modulates transcription.

Nucleic Acids Res. 2014; 42: 9666-9676. doi: 10.1093/nar/gku685.

Millán-Zambrano G, Chávez S

Nuclear functions of prefoldin

Open Biology. 2014; 4: 140085  doi: 10.1098/rsob.140085

Peñate X, Chávez S

RNA Polymerase II-Dependent Transcription in Fungi and Its Interplay with mRNA Decay

In “Fungal RNA Biology” (Sesma A and von der Haar T, eds.) 2014 Springer, ISBN: 978-3-319-05686-9 (Print) 978-3-319-05687-6 (Online)

Medina DA, Jordán-Pla A, Millán-Zambrano G, Chávez S, Choder M, Pérez-Ortín JE.

Cytoplasmic 5′-3′ exonuclease Xrn1p is also a genome-wide transcription factor in yeast

Frontiers in Genetics. 2014; 5:1. doi: 10.3389/fgene.2014.00001

Gaytán BD, Loguinov A, Peñate X, Lerot JM, Chávez S, Denslow N, Vulpe C

A Genome-Wide Screen Identifies Yeast Genes Required for Tolerance to Technical Toxaphene, an Organochlorinated Pesticide Mixture

PLoS One. 2013; 8:e81253.

Miguel A, Montón F, Li T, Gómez-Herreros F, Chávez S, Alepuz P, Pérez-Ortín JE.

External conditions inversely change the RNA polymerase II elongation rate and density in yeast

Biochim Biophys Acta. 2013; 1829: 1248-1255.

Gomez-Herreros F, Rodriguez-Galan O, Morillo-Huesca M, Maya D, Arista-Romero M, de la Cruz J, Chávez S, Muñoz-Centeno MC

Balanced production of ribosome components is required for proper G1/S transition in Saccharomyces cerevisiae.

J Biol Chem. 2013; 288: 31689-31700.

Pérez-Ortín JE, Medina DA, Chávez S, Moreno J

What do you mean by transcription rate?

Bioessays. 2013; 35: 1056-1062.

Millán-Zambrano G, Rodríguez-Gil A, Peñate X, de Miguel-Jiménez L, Morillo-Huesca M, Krogan N, Chávez S

The Prefoldin Complex Regulates Chromatin Dynamics during Transcription Elongation

PLoS Genetics. 2013; 9: e1003776.

Comment on this paper in the web of the “Saccharomyces genome database”:

A GLAMorous New Role for Prefoldin

Haimovich G, Medina DA, Causse SZ, Garber M, Millán-Zambrano G, Barkai O, Chávez S, Pérez-Ortín JE, Darzacq X, Choder M

Gene expression Is circular: factors for mRNA degradation also foster mRNA synthesis

Cell. 2013; 153: 1000-1011.

Pérez-Ortín JE, Alepuz P, Chávez S, Choder M.

Eukaryotic mRNA Decay: Methodologies, Pathways, and Links to Other Stages of Gene Expression.

J Mol Biol. 2013; 425: 3750-3775. 

Gómez-Herreros F, de Miguel-Jiménez L, Millán-Zambrano G, Peñate X, Delgado-Ramos L, Muñoz-Centeno MC,  Chávez S

One step back before moving forward: regulation of transcription elongation by arrest and backtracking.

FEBS Letters. 2012;  586: 2820-2825.

Gómez-Herreros F, de Miguel-Jiménez L, Morillo-Huesca M, Delgado-Ramos L, Muñoz-Centeno MC, Chávez S.

TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress.

Nucleic Acids Res. 2012; 40: 6508-6519.

Chávez S, Gross DS, Hermand D, Suñé C

Gene Control during Transcription Elongation.

Genetics Research International. 2012; 2012:ID758384.

García-Martínez J, Ayala G, Pelechano V, Chávez S, Herrero E, Pérez-Ortín JE.

The relative importance of transcription rate, cryptic transcription and mRNA stability on shaping stress responses in yeast.

Transcription. 2012; 3:39-44.

Muñoz-Centeno MC, Millán-Zambrano G, Chávez S.

A matter of packaging: influence of nucleosome positioning on heterologous gene expression.

Methods Mol Biol. 2012;824:51-64.

Pérez-Ortín JE, de Miguel-Jiménez L, Chávez S.

Genome-wide studies of mRNA synthesis and degradation in eukaryotes.

Biochim Biophys Acta. 2012; 1819:604-615.

Maya-Miles D, Morillo-Huesca M, Chávez S, Muñoz-CentenoMC.

Free histones and the cell cycle.

In “DNA replication - current advances”  H Seligmann (ed.), pp. 409-416; InTech, 2011

Gallastegui E, Millán-Zambrano G, Terme JM, Chávez S, Jordan A.

Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency.

J Virol. 2011; 85:3187-3202.

Martín-Banderas L, González-Prieto R, Rodríguez-Gil A, Fernández-Arévalo M, Flores-Mosquera M, Chávez S, Gañán-Calvo AM.

Application of Flow Focusing to the Break-Up of a Magnetite Suspension Jet for the Production of Paramagnetic Microparticles

Journal of Nanomaterials.  2011; 2011:ID 527437

Pelechano V, Chávez S, Pérez-Ortín JE.

A complete set of nascent transcription rates for yeast genes.

PLoS One. 2010; 5:e15442.

Morillo-Huesca M, Maya D, Muñoz-Centeno MC, Singh RK, Oreal V, Reddy GU, Liang D, Géli V, Gunjan A, Chávez S.

FACT prevents the accumulation of free histones evicted from transcribed chromatin and a subsequent cell cycle delay in G1.

PLoS Genet. 2010; 6:e1000964.

Rodríguez-Gil A, García-Martínez J, Pelechano V, Muñoz-Centeno Mde L, Geli V, Pérez-Ortín JE, Chávez S.

The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors.

Nucleic Acids Res. 2010; 38:4651-4664.

Pelechano V, Jimeno-González S, Rodríguez-Gil A, García-Martínez J, Pérez-Ortín JE, Chávez S.

Regulon-specific control of transcription elongation across the yeast genome.

PLoS Genet. 2009; 5:e1000614.

Gaillard H, Tous C, Botet J, González-Aguilera C, Quintero MJ, Viladevall L, García-Rubio ML, Rodríguez-Gil A, Marín A, Ariño J, Revuelta JL, Chávez S, Aguilera A.

Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair.

PLoS Genet. 2009; 5:e1000364.

Mas G, de Nadal E, Dechant R, Rodríguez de la Concepción ML, Logie C, Jimeno-González S, Chávez S, Ammerer G, Posas F.

Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes.

EMBO J. 2009; 28:326-36.

Vanti M, Gallastegui E, Respaldiza I, Rodríguez-Gil A, Gómez-Herreros F, Jimeno-González S, Jordan A, Chávez S.

Yeast genetic analysis reveals the involvement of chromatin reassembly factors in repressing HIV-1 basal transcription.

PLoS Genet. 2009; 5:e1000339.

Pascual-García P, Govind CK, Queralt E, Cuenca-Bono B, Llopis A, Chavez S, Hinnebusch AG, Rodríguez-Navarro S.

Sus1 is recruited to coding regions and functions during transcription elongation in association with SAGA and TREX2.

Genes Dev. 2008; 22:2811-2822.

Maya D, Quintero MJ, de la Cruz Muñoz-Centeno M, Chávez S.

Systems for applied gene control in Saccharomyces cerevisiae.

Biotechnol Lett. 2008; 30:979-987.

Quintero MJ, Maya D, Arévalo-Rodríguez M, Cebolla A, Chávez S.

An improved system for estradiol-dependent regulation of gene expression in yeast.

Microb Cell Fact. 2007; 6:10.

L. Martín-Banderas, A. Rodríguez-Gil, A. Cebolla, S. Chávez, Juan M. Fernández García, M. Flores-Mosquera and A. Gañán-Calvo

Towards a high throughput production of uniform encoded microparticles.

Advanced Materials. 2007; 18:559-564.

Dehé PM, Dichtl B, Schaft D, Roguev A, Pamblanco M, Lebrun R, Rodríguez-Gil A, Mkandawire M, Landsberg K, Shevchenko A, Shevchenko A, Rosaleny LE, Tordera V, Chávez S, Stewart AF, Géli V.

Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation.

J Biol Chem. 2006; 281:35404-35412.

Jimeno-González S, Gómez-Herreros F, Alepuz PM, Chávez S.

A gene-specific requirement for FACT during transcription is related to the chromatin organization of the transcribed region.

Mol Cell Biol. 2006; 26:8710-8721.

Gañán-Calvo AM, Martín-Banderas L, González-Prieto R, Rodríguez-Gil A, Berdún-Alvarez T, Cebolla A, Chávez S, Flores-Mosquera M.

Straightforward production of encoded microbeads by Flow Focusing: potential applications for biomolecule detection.

Int J Pharm. 2006; 324:19-26.

M. Morillo-Huesca, M. Vanti and S. Chávez

A simple in vivo assay for measuring the efficiency of gene length-dependent processes in yeast mRNA biogenesis.

FEBS Journal. 2006; 273: 756-769.

Trésaugues L, Dehé PM, Guérois R, Rodriguez-Gil A, Varlet I, Salah P, Pamblanco M, Luciano P, Quevillon-Cheruel S, Sollier J, Leulliot N, Couprie J, Tordera V, Zinn-Justin S, Chàvez S, van Tilbeurgh H, Géli V.

Structural characterization of Set1 RNA recognition motifs and their role in histone H3 lysine 4 methylation.

J Mol Biol. 2006; 359:1170-1181.

L. Martín-Banderas, M. Flores-Mosquera, P. Riesco-Chueca, A. Rodríguez-Gil, A. Cebolla, S. Chávez and A. Gañán-Calvo.

Flow Focusing: A versatile technology to produce size-controlled and specific-morphology microparticles.

Small 2005; 1: 688-692.

S. Chávez (Editor) et al. (2005)

Perspectivas en Genética y Biomedicina

(ISBN 84-9756-332-8) Editorial Síntesis, Madrid.

L. Montoliu, S. Chávez and M. Vidal

Variegation associated with lacZ in transgenic animals: a warning note.

Transgenic Research 9: 237-239.