{"id":33,"date":"2024-10-01T19:30:00","date_gmt":"2024-10-01T17:30:00","guid":{"rendered":"http:\/\/grupo.us.es\/dgclab\/?page_id=33"},"modified":"2024-10-01T23:00:10","modified_gmt":"2024-10-01T21:00:10","slug":"publicaciones","status":"publish","type":"page","link":"http:\/\/grupo.us.es\/dgclab\/publicaciones\/","title":{"rendered":"Publicaciones"},"content":{"rendered":"\n

Publicaciones<\/strong><\/p>\n\n\n\n

MDC1 maintains active elongation complexes of RNA polymerase II<\/strong>. Pappas G, Nesgaard SH, Watanabe K, Hagner H, Lee M, Gomez-Cabello D, Kanellis DC, Olivares-Chauvet P, Larsen DH, Gregersen L, Maya-Mendoza A, Galanos P, Bartek J. Cell Reports, 42 (1); 111979 (2022). https:\/\/doi.org\/10.1016\/j.celrep.2022.111979<\/a><\/p>\n\n\n\n

CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway. <\/strong><\/a>G\u00f3mez-Cabello D<\/a>* (co-corresponding author)<\/em>, Pappas, G., Aguilar-Morante, D. et al.<\/em> CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway. Nat Commun<\/em> 13, 5303 (2022). https:\/\/doi.org\/10.1038\/s41467-022-33027-z<\/a><\/p>\n\n\n\n

Therapeutic Opportunities of Disrupting Genome Integrity in Adult Diffuse Glioma<\/strong><\/a>. Aguilar-Morante, Diana; G\u00f3mez-Cabello, Daniel<\/a>; Quek, Hazel; Liu, Tianqing; Hamerlik, Petra; Lim, Yi Chieh. 2022 Biomedicines (2227-9059). https:\/\/doi.org\/10.3390\/biomedicines10020332<\/a><\/p>\n\n\n\n

Methylation of the central transcriptional regulator KLF4 by PRMT5 is required for DNA end resection and recombination.<\/strong><\/a> Checa-Rodr\u00edguez C, Cepeda-Garc\u00eda C, Ram\u00f3n J, L\u00f3pez-Saavedra A, Balestra FR, Dom\u00ednguez-S\u00e1nchez MS, G\u00f3mez-Cabello D, Huertas P.DNA Repair (Amst). 2020 Oct;94:102902. doi: 10.1016\/j.dnarep.2020.102902<\/a>.<\/p>\n\n\n\n

CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells.<\/strong><\/a> G\u00f3mez-Cabello D<\/a>(co-corresponding author)<\/em><\/strong>, Checa-Rodr\u00edguez C, Abad M, Serrano M, Huertas P.Stem Cell Reports. 2017 Feb 14;8(2):432-445. doi: 10.1016\/j.stemcr.2016.12.009<\/a>.<\/p>\n\n\n\n

A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.<\/strong><\/a> L\u00f3pez-Saavedra A, G\u00f3mez-Cabello D<\/a>, Dom\u00ednguez-S\u00e1nchez MS, Mej\u00edas-Navarro F, Fern\u00e1ndez-\u00c1vila MJ, Dinant C, Mart\u00ednez-Mac\u00edas MI, Bartek J, Huertas P.Nat Commun. 2016 Aug 9;7:12364. doi: 10.1038\/ncomms12364.PMID: 27503537 <\/a><\/p>\n\n\n\n

Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break <\/strong><\/a>repair pathway choice.<\/strong><\/a> <\/strong>Jimeno S, Fern\u00e1ndez-\u00c1vila MJ, Cruz-Garc\u00eda A, Cepeda-Garc\u00eda C, G\u00f3mez-Cabello D<\/a>, Huertas P.Nucleic Acids Res. 2015 Jan;43(2):987-99. doi: 10.1093\/nar\/gku1384. Epub 2015 Jan 7.PMID: 25567988<\/p>\n\n\n\n

New tools to study DNA double-strand break repair pathway choice.<\/strong><\/a> Gomez-Cabello D,<\/a> Jimeno S, Fern\u00e1ndez-\u00c1vila MJ, Huertas P.PLoS One. 2013 Oct 14;8(10):e77206. doi: 10.1371\/journal.pone.0077206. eCollection 2013.PMID: 24155929<\/p>\n\n\n\n

microRNA biogenesis and senescence.<\/strong><\/a> G\u00f3mez-Cabello D<\/a>, Adrados I, Palmero I.Aging (Albany NY). 2013 Oct;5(10):721-2. doi: 10.18632\/aging.100607.PMID: 24142392 <\/p>\n\n\n\n

DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts.<\/strong> <\/a>G\u00f3mez-Cabello D, Adrados I, Gamarra D, Kobayashi H, Takatsu Y, Takatsu K, Gil J, Palmero I.Aging Cell. 2013 Oct;12(5):923-31. doi: 10.1111\/acel.12117. Epub 2013 Jul 19.PMID: 23773483<\/p>\n\n\n\n

Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer.<\/strong><\/a> Oliveras G, Blancafort A, Urruticoechea A, Campuzano O, G\u00f3mez-Cabello D<\/a>, Brugada R, L\u00f3pez-Rodr\u00edguez ML, Colomer R, Puig T.Ann N Y Acad Sci. 2010 Oct;1210:86-92. doi: 10.1111\/j.1749-6632.2010.05777.x.PMID: 20973802<\/p>\n\n\n\n

Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1.<\/strong><\/a> G\u00f3mez-Cabello D<\/a>, Callejas S, Bengur\u00eda A, Moreno A, Alonso J, Palmero I.Cancer Res. 2010 Mar 1;70(5):1866-74. doi: 10.1158\/0008-5472.CAN-09-2088. Epub 2010 Feb 23.PMID: 20179197<\/p>\n\n\n\n

Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells. <\/strong><\/a>Jin Q, Yuan LX, Boulbes D, Baek JM, Wang YN, Gomez-Cabello D<\/a>, Hawke DH, Yeung SC, Lee MH, Hortobagyi GN, Hung MC, Esteva FJ.Breast Cancer Res. 2010;12(6):R96. doi: 10.1186\/bcr2777. Epub 2010 Nov 16.PMID: 21080941 <\/p>\n\n\n\n

ING proteins in cellular senescence.<\/strong><\/a> Men\u00e9ndez C, Abad M, G\u00f3mez-Cabello D<\/a>, Moreno A, Palmero I.Curr Drug Targets. 2009 May;10(5):406-17. doi: 10.2174\/138945009788185077.PMID: 19442113 Review.<\/p>\n","protected":false},"excerpt":{"rendered":"

Publicaciones MDC1 maintains active elongation complexes of RNA polymerase II. Pappas G, Nesgaard SH, Watanabe K, Hagner H, Lee M, Gomez-Cabello D, Kanellis DC, Olivares-Chauvet P, Larsen DH, Gregersen L, Maya-Mendoza A, Galanos P, Bartek J. Cell Reports, 42 (1); 111979 (2022). https:\/\/doi.org\/10.1016\/j.celrep.2022.111979 CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-33","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/grupo.us.es\/dgclab\/wp-json\/wp\/v2\/pages\/33","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/grupo.us.es\/dgclab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/grupo.us.es\/dgclab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/grupo.us.es\/dgclab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/grupo.us.es\/dgclab\/wp-json\/wp\/v2\/comments?post=33"}],"version-history":[{"count":3,"href":"http:\/\/grupo.us.es\/dgclab\/wp-json\/wp\/v2\/pages\/33\/revisions"}],"predecessor-version":[{"id":132,"href":"http:\/\/grupo.us.es\/dgclab\/wp-json\/wp\/v2\/pages\/33\/revisions\/132"}],"wp:attachment":[{"href":"http:\/\/grupo.us.es\/dgclab\/wp-json\/wp\/v2\/media?parent=33"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}