Publicaciones
MDC1 maintains active elongation complexes of RNA polymerase II. Pappas G, Nesgaard SH, Watanabe K, Hagner H, Lee M, Gomez-Cabello D, Kanellis DC, Olivares-Chauvet P, Larsen DH, Gregersen L, Maya-Mendoza A, Galanos P, Bartek J. Cell Reports, 42 (1); 111979 (2022). https://doi.org/10.1016/j.celrep.2022.111979
CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway. Gómez-Cabello D* (co-corresponding author), Pappas, G., Aguilar-Morante, D. et al. CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway. Nat Commun 13, 5303 (2022). https://doi.org/10.1038/s41467-022-33027-z
Therapeutic Opportunities of Disrupting Genome Integrity in Adult Diffuse Glioma. Aguilar-Morante, Diana; Gómez-Cabello, Daniel; Quek, Hazel; Liu, Tianqing; Hamerlik, Petra; Lim, Yi Chieh. 2022 Biomedicines (2227-9059). https://doi.org/10.3390/biomedicines10020332
Methylation of the central transcriptional regulator KLF4 by PRMT5 is required for DNA end resection and recombination. Checa-Rodríguez C, Cepeda-García C, Ramón J, López-Saavedra A, Balestra FR, Domínguez-Sánchez MS, Gómez-Cabello D, Huertas P.DNA Repair (Amst). 2020 Oct;94:102902. doi: 10.1016/j.dnarep.2020.102902.
CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells. Gómez-Cabello D(co-corresponding author), Checa-Rodríguez C, Abad M, Serrano M, Huertas P.Stem Cell Reports. 2017 Feb 14;8(2):432-445. doi: 10.1016/j.stemcr.2016.12.009.
A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection. López-Saavedra A, Gómez-Cabello D, Domínguez-Sánchez MS, Mejías-Navarro F, Fernández-Ávila MJ, Dinant C, Martínez-Macías MI, Bartek J, Huertas P.Nat Commun. 2016 Aug 9;7:12364. doi: 10.1038/ncomms12364.PMID: 27503537
Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice. Jimeno S, Fernández-Ávila MJ, Cruz-García A, Cepeda-García C, Gómez-Cabello D, Huertas P.Nucleic Acids Res. 2015 Jan;43(2):987-99. doi: 10.1093/nar/gku1384. Epub 2015 Jan 7.PMID: 25567988
New tools to study DNA double-strand break repair pathway choice. Gomez-Cabello D, Jimeno S, Fernández-Ávila MJ, Huertas P.PLoS One. 2013 Oct 14;8(10):e77206. doi: 10.1371/journal.pone.0077206. eCollection 2013.PMID: 24155929
microRNA biogenesis and senescence. Gómez-Cabello D, Adrados I, Palmero I.Aging (Albany NY). 2013 Oct;5(10):721-2. doi: 10.18632/aging.100607.PMID: 24142392
DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts. Gómez-Cabello D, Adrados I, Gamarra D, Kobayashi H, Takatsu Y, Takatsu K, Gil J, Palmero I.Aging Cell. 2013 Oct;12(5):923-31. doi: 10.1111/acel.12117. Epub 2013 Jul 19.PMID: 23773483
Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer. Oliveras G, Blancafort A, Urruticoechea A, Campuzano O, Gómez-Cabello D, Brugada R, López-Rodríguez ML, Colomer R, Puig T.Ann N Y Acad Sci. 2010 Oct;1210:86-92. doi: 10.1111/j.1749-6632.2010.05777.x.PMID: 20973802
Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1. Gómez-Cabello D, Callejas S, Benguría A, Moreno A, Alonso J, Palmero I.Cancer Res. 2010 Mar 1;70(5):1866-74. doi: 10.1158/0008-5472.CAN-09-2088. Epub 2010 Feb 23.PMID: 20179197
Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells. Jin Q, Yuan LX, Boulbes D, Baek JM, Wang YN, Gomez-Cabello D, Hawke DH, Yeung SC, Lee MH, Hortobagyi GN, Hung MC, Esteva FJ.Breast Cancer Res. 2010;12(6):R96. doi: 10.1186/bcr2777. Epub 2010 Nov 16.PMID: 21080941
ING proteins in cellular senescence. Menéndez C, Abad M, Gómez-Cabello D, Moreno A, Palmero I.Curr Drug Targets. 2009 May;10(5):406-17. doi: 10.2174/138945009788185077.PMID: 19442113 Review.